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5t4x
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==CRYSTAL STRUCTURE OF PDE6D IN APO-STATE== | |
| - | + | <StructureSection load='5t4x' size='340' side='right' caption='[[5t4x]], [[Resolution|resolution]] 1.81Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5t4x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T4X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t4x OCA], [http://pdbe.org/5t4x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t4x RCSB], [http://www.ebi.ac.uk/pdbsum/5t4x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t4x ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| - | [[Category: Qureshi, B | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/PDE6D_MOUSE PDE6D_MOUSE]] Promotes the release of prenylated target proteins from cellular membranes (PubMed:22179043). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22179043). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (By similarity). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (PubMed:22179043). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.[UniProtKB:O43924][UniProtKB:Q95142]<ref>PMID:10518933</ref> <ref>PMID:15979089</ref> <ref>PMID:22179043</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Qureshi, B M]] | ||
| + | [[Category: Scheerer, P]] | ||
[[Category: Schmidt, A]] | [[Category: Schmidt, A]] | ||
| - | [[Category: | + | [[Category: Apo-state]] |
| + | [[Category: Cellular trafficking]] | ||
| + | [[Category: Farnesyl]] | ||
| + | [[Category: Geranylgeranyl]] | ||
| + | [[Category: Immunoglobulin-like beta sandwitch]] | ||
| + | [[Category: Lipid binding protein]] | ||
| + | [[Category: Membrane dissociation]] | ||
| + | [[Category: Membrane trafficking]] | ||
| + | [[Category: Pde6 delta]] | ||
| + | [[Category: Phosphodiesterase 6]] | ||
| + | [[Category: Prenyl binding protein]] | ||
| + | [[Category: Ras-gtpase]] | ||
| + | [[Category: Rhodopsin]] | ||
| + | [[Category: Rhodopsin kinase]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 08:25, 10 January 2018
CRYSTAL STRUCTURE OF PDE6D IN APO-STATE
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Categories: Qureshi, B M | Scheerer, P | Schmidt, A | Apo-state | Cellular trafficking | Farnesyl | Geranylgeranyl | Immunoglobulin-like beta sandwitch | Lipid binding protein | Membrane dissociation | Membrane trafficking | Pde6 delta | Phosphodiesterase 6 | Prenyl binding protein | Ras-gtpase | Rhodopsin | Rhodopsin kinase | Transport protein
