This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Spectrin
From Proteopedia
(Difference between revisions)
| Line 30: | Line 30: | ||
* Spectrin α | * Spectrin α | ||
| + | **[[2kr3]], [[4f17]], [[4f16]] - cSPTA SH3 domain<br /> | ||
| + | **[[1e6g]], [[1e6h]], [[1hd3]], [[1qkx]], [[1pwt]], [[1bk2]], [[1shg]], [[1h8k]], [[3ngp]], [[3m0p]], [[3m0q]], [[3m0r]], [[3m0s]], [[3m0t]], [[3m0u]] - cSPTA SH3 domain (mutant)<br /> | ||
**[[1uue]], [[1e7o]], [[1g2b]], [[1aey]], [[1tuc]], [[1tud]] - cSPTA SH3 domain (mutant) – NMR<br /> | **[[1uue]], [[1e7o]], [[1g2b]], [[1aey]], [[1tuc]], [[1tud]] - cSPTA SH3 domain (mutant) – NMR<br /> | ||
**[[2lj3]] - cSPTA SH3 domain – NMR<br /> | **[[2lj3]] - cSPTA SH3 domain – NMR<br /> | ||
| - | **[[1e6g]], [[1e6h]], [[1hd3]], [[1qkx]], [[1pwt]], [[1bk2]], [[1shg]] - cSPTA SH3 domain (mutant)<br /> | ||
**[[1u4q]] – cSPTA repeats 15-17 <br /> | **[[1u4q]] – cSPTA repeats 15-17 <br /> | ||
**[[1u5p]] - cSPTA repeats 15-16<br /> | **[[1u5p]] - cSPTA repeats 15-16<br /> | ||
| Line 38: | Line 39: | ||
**[[1aj3]] - cSPTA repeat 16 - NMR<br /> | **[[1aj3]] - cSPTA repeat 16 - NMR<br /> | ||
**[[1owa]] - hSPTA tetramerization domain – NMR<br /> | **[[1owa]] - hSPTA tetramerization domain – NMR<br /> | ||
| - | **[[ | + | **[[5j4o]] - hSPTA repeats 16-17<br /> |
| - | + | ||
* Spectrin β1 | * Spectrin β1 | ||
Revision as of 17:14, 5 October 2017
| |||||||||||
3D Structures of Spectrin
Updated on 05-October-2017
References
- ↑ Das A, Base C, Dhulipala S, Dubreuil RR. Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. J Cell Biol. 2006 Oct 23;175(2):325-35. PMID:17060500 doi:http://dx.doi.org/10.1083/jcb.200602095
- ↑ Coetzer T, Palek J, Lawler J, Liu SC, Jarolim P, Lahav M, Prchal JT, Wang W, Alter BP, Schewitz G, et al.. Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis. Blood. 1990 Jun 1;75(11):2235-44. PMID:2346784
- ↑ Dhermy D, Galand C, Bournier O, Cynober T, Mechinaud F, Tchemia G, Garbarz M. Hereditary spherocytosis with spectrin deficiency related to null mutations of the beta-spectrin gene. Blood Cells Mol Dis. 1998 Jun;24(2):251-61. PMID:9714702 doi:http://dx.doi.org/10.1006/bcmd.1998.0190
