User:Alec Bertsch/sandbox 1
From Proteopedia
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==L5/5S rRNA Complex== | ==L5/5S rRNA Complex== | ||
<StructureSection load='1mji' size='340' side='right' caption='Caption for this structure' scene=''> | <StructureSection load='1mji' size='340' side='right' caption='Caption for this structure' scene=''> | ||
| - | The | + | The ribosome is an essential component of all living cells. It is responsible for translation of proteins using messenger RNA (mRNA) and transfer RNA (tRNA). Ribosomes are composed of both proteins and RNA known as ribosomal RNA (rRNA). There are three functional sites found within the ribosome that are essential for translation: the A, P, and E-sites. The A-site is responsible for recruiting the tRNA and the E-site is where the tRNA leaves from once the protein is removed in the P-site. The site of interest for this sandbox is the P-site, where the protein is removed from the tRNA and added to the growing chain of amino acids. Its primary component is the L5/5S rRNA complex. |
This is a default text for your page '''Alec Bertsch/sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Alec Bertsch/sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Function == | == Function == | ||
| - | + | The L5 protein is also responsible for the assembly of the ribosome. In ribosomes that fail to synthesize the L5 protein, the ribosome is unable to connect the large and small units together. | |
== Disease == | == Disease == | ||
Revision as of 00:59, 10 October 2017
L5/5S rRNA Complex
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
