1ygo

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[[Image:1ygo.gif|left|200px]]
[[Image:1ygo.gif|left|200px]]
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{{Structure
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|PDB= 1ygo |SIZE=350|CAPTION= <scene name='initialview01'>1ygo</scene>
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The line below this paragraph, containing "STRUCTURE_1ygo", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND=
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span>
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|GENE= pll ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])
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{{STRUCTURE_1ygo| PDB=1ygo | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ygo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ygo OCA], [http://www.ebi.ac.uk/pdbsum/1ygo PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ygo RCSB]</span>
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'''Solution Structure of the pelle Death Domain'''
'''Solution Structure of the pelle Death Domain'''
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[[Category: Moncrieffe, M C.]]
[[Category: Moncrieffe, M C.]]
[[Category: Stott, K M.]]
[[Category: Stott, K M.]]
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[[Category: anti-parallel 6 helix bundle]]
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[[Category: Anti-parallel 6 helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 16:17:37 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:06:46 2008''
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Revision as of 13:17, 3 May 2008

Image:1ygo.gif

Template:STRUCTURE 1ygo

Solution Structure of the pelle Death Domain


Overview

The interaction between the death domains (DDs) of Tube and the protein kinase Pelle is an important component of the Toll pathway. Published crystallographic data suggests that the Pelle-Tube DD interface is plastic and implies that in addition to the two predominant Pelle-Tube interfaces, a third interaction is possible. We present the NMR solution structure of the isolated death domain of Pelle and a study of the interaction between the DDs of Pelle and Tube. Our data suggests the solution structure of the isolated Pelle DD is similar to that of Pelle DD in complex with Tube. Additionally, they suggest that the plasticity observed in the crystal structure may not be relevant in the functioning death domain complex.

About this Structure

1YGO is a Single protein structure of sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

Solution structure of the isolated Pelle death domain., Moncrieffe MC, Stott KM, Gay NJ, FEBS Lett. 2005 Jul 18;579(18):3920-6. PMID:16004997 Page seeded by OCA on Sat May 3 16:17:37 2008

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