1yho

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[[Image:1yho.gif|left|200px]]
[[Image:1yho.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1yho |SIZE=350|CAPTION= <scene name='initialview01'>1yho</scene>
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The line below this paragraph, containing "STRUCTURE_1yho", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=TRR:2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM'>TRR</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1yho| PDB=1yho | SCENE= }}
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|RELATEDENTRY=[[1kms|1KMS]], [[1kmv|1KMV]], [[1lud|1LUD]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yho OCA], [http://www.ebi.ac.uk/pdbsum/1yho PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1yho RCSB]</span>
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}}
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'''Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures'''
'''Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures'''
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[[Category: Birdsall, B.]]
[[Category: Birdsall, B.]]
[[Category: Polshakov, V I.]]
[[Category: Polshakov, V I.]]
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[[Category: dhfr]]
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[[Category: Dhfr]]
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[[Category: inhibitor/enzyme complex]]
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[[Category: Inhibitor/enzyme complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 16:19:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:07:36 2008''
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Revision as of 13:19, 3 May 2008

Template:STRUCTURE 1yho

Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures


About this Structure

1YHO is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH., Kovalevskaya NV, Smurnyy YD, Polshakov VI, Birdsall B, Bradbury AF, Frenkiel T, Feeney J, J Biomol NMR. 2005 Sep;33(1):69-72. PMID:16222560 Page seeded by OCA on Sat May 3 16:19:49 2008

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