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2zy5
From Proteopedia
(Difference between revisions)
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==R487A mutant of L-aspartate beta-decarboxylase== | ==R487A mutant of L-aspartate beta-decarboxylase== | ||
| - | <StructureSection load='2zy5' size='340' side='right' caption='[[2zy5]], [[Resolution|resolution]] 2.65Å' scene=''> | + | <StructureSection load='2zy5' size='340' side='right'caption='[[2zy5]], [[Resolution|resolution]] 2.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2zy5]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2zy5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/'alcaligenes_odorans' 'alcaligenes odorans']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZY5 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zy2|2zy2]], [[2zy3|2zy3]], [[2zy4|2zy4]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zy2|2zy2]], [[2zy3|2zy3]], [[2zy4|2zy4]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">asdA-AF ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">asdA-AF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32001 'Alcaligenes odorans'])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aspartate_4-decarboxylase Aspartate 4-decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.12 4.1.1.12] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zy5 OCA], [https://pdbe.org/2zy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zy5 RCSB], [https://www.ebi.ac.uk/pdbsum/2zy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zy5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/ASDA_COMTE ASDA_COMTE]] Bifunctional enzyme that has both L-aspartate decarboxylase and transaminase activity.<ref>PMID:19368885</ref> [PDB:2ZY3] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/2zy5_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zy/2zy5_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2zy5" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2zy5" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Aspartate decarboxylase 3D structures|Aspartate decarboxylase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Alcaligenes odorans]] | [[Category: Alcaligenes odorans]] | ||
[[Category: Aspartate 4-decarboxylase]] | [[Category: Aspartate 4-decarboxylase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Chen, H J]] | [[Category: Chen, H J]] | ||
[[Category: Ko, T P]] | [[Category: Ko, T P]] | ||
Revision as of 07:20, 10 November 2021
R487A mutant of L-aspartate beta-decarboxylase
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