1zm7

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==Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP==
==Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP==
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<StructureSection load='1zm7' size='340' side='right' caption='[[1zm7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1zm7' size='340' side='right'caption='[[1zm7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zm7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZM7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZM7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zm7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZM7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1ZM7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TTP:THYMIDINE-5-TRIPHOSPHATE'>TTP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1j90|1j90]], [[1oe0|1oe0]], [[1ot3|1ot3]], [[1zmx|1zmx]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1j90|1j90]], [[1oe0|1oe0]], [[1ot3|1ot3]], [[1zmx|1zmx]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zm7 OCA], [http://pdbe.org/1zm7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zm7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zm7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zm7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1zm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zm7 OCA], [http://pdbe.org/1zm7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zm7 RCSB], [http://www.ebi.ac.uk/pdbsum/1zm7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zm7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zm/1zm7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zm/1zm7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1zm7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1zm7" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Thymidine kinase|Thymidine kinase]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Deoxynucleoside kinase]]
[[Category: Deoxynucleoside kinase]]
[[Category: Drome]]
[[Category: Drome]]
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[[Category: Large Structures]]
[[Category: Berenstein, D]]
[[Category: Berenstein, D]]
[[Category: Eklund, H]]
[[Category: Eklund, H]]

Revision as of 09:06, 20 January 2021

Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP

PDB ID 1zm7

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