2fiq

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==Crystal structure of putative tagatose 6-phosphate kinase==
==Crystal structure of putative tagatose 6-phosphate kinase==
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<StructureSection load='2fiq' size='340' side='right' caption='[[2fiq]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='2fiq' size='340' side='right'caption='[[2fiq]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2fiq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Eco57 Eco57]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FIQ FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FIQ FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fiq OCA], [https://pdbe.org/2fiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fiq RCSB], [https://www.ebi.ac.uk/pdbsum/2fiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fiq ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2fiq TOPSAN]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECs2898 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83334 ECO57])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tagatose_kinase Tagatose kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.101 2.7.1.101] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fiq OCA], [http://pdbe.org/2fiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fiq RCSB], [http://www.ebi.ac.uk/pdbsum/2fiq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fiq ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2fiq TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/GATZ_ECOLI GATZ_ECOLI]] Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol.<ref>PMID:8955298</ref> <ref>PMID:11976750</ref>
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/2fiq_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/2fiq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fiq ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fiq ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Eco57]]
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[[Category: Large Structures]]
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[[Category: Tagatose kinase]]
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[[Category: Almo SC]]
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[[Category: Almo, S C]]
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[[Category: Burley SK]]
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[[Category: Burley, S K]]
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[[Category: Fedorov E]]
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[[Category: Fedorov, E]]
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[[Category: Ramagopal UA]]
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[[Category: Structural genomic]]
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[[Category: Ramagopal, U A]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Transferase]]
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Revision as of 15:27, 3 March 2021

Crystal structure of putative tagatose 6-phosphate kinase

PDB ID 2fiq

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