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2h2r

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==Crystal structure of the human CD23 Lectin domain, apo form==
==Crystal structure of the human CD23 Lectin domain, apo form==
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<StructureSection load='2h2r' size='340' side='right' caption='[[2h2r]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='2h2r' size='340' side='right'caption='[[2h2r]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2h2r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H2R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2h2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H2R FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2h2t|2h2t]], [[1t8d|1t8d]], [[1t8c|1t8c]], [[1kje|1kje]], [[1hli|1hli]], [[1hlj|1hlj]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2h2t|2h2t]], [[1t8d|1t8d]], [[1t8c|1t8c]], [[1kje|1kje]], [[1hli|1hli]], [[1hlj|1hlj]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FCER2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FCER2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h2r OCA], [http://pdbe.org/2h2r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h2r RCSB], [http://www.ebi.ac.uk/pdbsum/2h2r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2h2r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h2r OCA], [https://pdbe.org/2h2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h2r RCSB], [https://www.ebi.ac.uk/pdbsum/2h2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h2r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN]] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
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[[https://www.uniprot.org/uniprot/FCER2_HUMAN FCER2_HUMAN]] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/2h2r_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/2h2r_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 2h2r" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2h2r" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[CD23|CD23]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Wurzburg, B A]]
[[Category: Wurzburg, B A]]
[[Category: Apo form]]
[[Category: Apo form]]

Revision as of 07:29, 17 March 2021

Crystal structure of the human CD23 Lectin domain, apo form

PDB ID 2h2r

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