2nmm
From Proteopedia
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==Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409==  | ==Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409==  | ||
| - | <StructureSection load='2nmm' size='340' side='right' caption='[[2nmm]], [[Resolution|resolution]] 2.70Å' scene=''>  | + | <StructureSection load='2nmm' size='340' side='right'caption='[[2nmm]], [[Resolution|resolution]] 2.70Å' scene=''>  | 
== Structural highlights ==  | == Structural highlights ==  | ||
| - | <table><tr><td colspan='2'>[[2nmm]] is a 3 chain structure with sequence from [  | + | <table><tr><td colspan='2'>[[2nmm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NMM FirstGlance]. <br>  | 
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>  | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>  | 
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>  | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>  | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHPT1, PHP14 ([  | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHPT1, PHP14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>  | 
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[  | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nmm OCA], [https://pdbe.org/2nmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nmm RCSB], [https://www.ebi.ac.uk/pdbsum/2nmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nmm ProSAT], [https://www.topsan.org/Proteins/NESGC/2nmm TOPSAN]</span></td></tr>  | 
</table>  | </table>  | ||
== Function ==  | == Function ==  | ||
| - | [[  | + | [[https://www.uniprot.org/uniprot/PHP14_HUMAN PHP14_HUMAN]] Exhibits phosphohistidine phosphatase activity.   | 
== Evolutionary Conservation ==  | == Evolutionary Conservation ==  | ||
[[Image:Consurf_key_small.gif|200px|right]]  | [[Image:Consurf_key_small.gif|200px|right]]  | ||
Check<jmol>  | Check<jmol>  | ||
  <jmolCheckbox>  |   <jmolCheckbox>  | ||
| - |     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/2nmm_consurf.spt"</scriptWhenChecked>  | + |     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/2nmm_consurf.spt"</scriptWhenChecked>  | 
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  |     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>  | ||
    <text>to colour the structure by Evolutionary Conservation</text>  |     <text>to colour the structure by Evolutionary Conservation</text>  | ||
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</StructureSection>  | </StructureSection>  | ||
[[Category: Human]]  | [[Category: Human]]  | ||
| + | [[Category: Large Structures]]  | ||
[[Category: Abashidze, M]]  | [[Category: Abashidze, M]]  | ||
[[Category: Acton, T]]  | [[Category: Acton, T]]  | ||
Revision as of 15:45, 8 June 2021
Crystal structure of human phosphohistidine phosphatase. Northeast Structural Genomics Consortium target HR1409
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Categories: Human | Large Structures | Abashidze, M | Acton, T | Conover, K | Cunningham, K | Fang, Y | Forouhar, F | Hunt, J F | Kent, C | Kuzin, A P | Ma, L C | Montelione, G | Structural genomic | Seetharaman, J | Tong, L | Xiao, R | Hydrolase | Nesg q9h0y3 human phosphohistidine phosphatase | PSI, Protein structure initiative

