Cytochrome bc1 complex

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== Structural highlights ==
== Structural highlights ==
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Cbc1 is a <scene name='49/490879/Cv/3'>dimeric protein</scene> composed of 11 proteins and cofactors which include heme-carrying proteins like <scene name='49/490879/Cv/2'>cytochrome b (Cb)</scene> and <scene name='49/490879/Cv/4'>cytochrome c1 (Cc1)</scene> and iron-sulfur cluster proteins like <scene name='49/490879/Cv/5'>Rieske Fe-S protein (RISP)</scene>. The iron containing moieties are <scene name='49/490879/Cv/8'>heme</scene>, <scene name='49/490879/Cv/9'>heme C</scene> (where vinyl side chain of heme are replaced by thioether) and <scene name='49/490879/Cv/10'>Fe2S2</scene>. <ref>PMID:16034531</ref>
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Cbc1 is a <scene name='49/490879/Cv/11'>dimeric protein</scene> composed of 11 proteins and cofactors which include heme-carrying proteins like <scene name='49/490879/Cv/12'>cytochrome b (Cb)</scene> and <scene name='49/490879/Cv/13'>cytochrome c1 (Cc1)</scene> and iron-sulfur cluster proteins like <scene name='49/490879/Cv/14'>Rieske Fe-S protein (RISP)</scene>. The iron containing moieties are <scene name='49/490879/Cv/15'>heme</scene>, <scene name='49/490879/Cv/16'>heme C</scene> (where vinyl side chain of heme are replaced by thioether) and <scene name='49/490879/Cv/17'>Fe2S2</scene>. <ref>PMID:16034531</ref>
</StructureSection>
</StructureSection>
==3D structures of cytochrome bc1==
==3D structures of cytochrome bc1==

Revision as of 07:46, 18 February 2019

Cytochrome bc1 containing Cb (green), Cc1 (yellow), RISP (beige) and Fe2S2 complex with stigmatellin (PDB entry 1zrt)

Drag the structure with the mouse to rotate

3D structures of cytochrome bc1

Updated on 18-February-2019

2fyn - RsCb (mutant) + Cc1 + RISP – Rhodobacter sphaeroides
1zrt - Cb + Cc1 + RISP – Rhodobacter capsulatus
1bgy, 1be3, 1l0n, 1ntm - bCb + bCc1 + RISP – bovine
1qcr - bCb + bCc1 + RISP – Cα model
1sqp, 2fyu, 1l0l, 1ntk, 1pp9, 1ppj, 1sqb, 2a06, 1sqv, 1sqx, 1sqq - bCb + bCc1 + RISP + inhibitor
4d6u - bCb + bCc1 + RISP + antimalarial pyridone
1ntz - bCb + bCc1 + RISP + ubiquinone
1nu1 - bCb + bCc1 + RISP + quinolone derivative
2qjk - RsCb (mutant) + RsCc1 + RISP + inhibitor
2qjp - RsCb + RsCc1 + RISP + inhibitor
2qjy - RsCb (mutant) + RsCc1 + RISP (mutant) + inhibitor
2ibz, 1kyo, 1kb9, 1p84 - yCb + yCc1 + RISP + inhibitor - yeast
3cx5 - yCb + yCc1 + RISP
1ezv - yCb + yCc1 + RISP + antibody
2yiu - Cb + Cc1 + RISP – Paracoccus denitrificans
1qcr - bCb + bCc1 + RISP – bovine – Cα model
3cxh, 3h1h, 1bcc, 3h1h - cCb + cCc1 + RISP - chicken
3cwb, 3h1i, 3h1j, 3h1k, 3h1l, 3l70, 3l71, 3l72, 3l73, 3l74, 3l75, 3tgu, 3bcc, 2bcc, 3h1i - cCb + cCc1 + RISP + inhibitor


References

  1. ↑ Crofts AR. The cytochrome bc1 complex: function in the context of structure. Annu Rev Physiol. 2004;66:689-733. PMID:14977419 doi:http://dx.doi.org/10.1146/annurev.physiol.66.032102.150251
  2. ↑ Berry EA, Huang LS, Saechao LK, Pon NG, Valkova-Valchanova M, Daldal F. X-Ray Structure of Rhodobacter Capsulatus Cytochrome bc (1): Comparison with its Mitochondrial and Chloroplast Counterparts. Photosynth Res. 2004;81(3):251-75. PMID:16034531 doi:http://dx.doi.org/10.1023/B:PRES.0000036888.18223.0e
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