Formyl-CoA transferase
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
| - | FCT structure shows <scene name='59/593959/Cv/2'>2 domains: large and small</scene>. The large domain is composed of residues from the N-terminal and the C-terminal. The active site binds <scene name='59/593959/Cv/ | + | FCT structure shows <scene name='59/593959/Cv/2'>2 domains: large and small</scene>. The large domain is composed of residues from the N-terminal and the C-terminal. The active site binds <scene name='59/593959/Cv/10'>oxalate</scene>, <scene name='59/593959/Cv/11'>Cl</scene> and <scene name='59/593959/Cv/12'>CoA</scene> <ref>PMID:18162462</ref>. Water molecules are shown as red spheres. |
</StructureSection> | </StructureSection> | ||
==3D structures of formyl-CoA transferase== | ==3D structures of formyl-CoA transferase== | ||
Current revision
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3D structures of formyl-CoA transferase
Updated on 28-March-2019
1p5h – OfFCT – Oxalobacter formigenes
1t3z, 2vjn, 2vjp, 2vjq – OfFCT (mutant)
1p5r, 2vjk, 2vjl – OfFCT + CoA
1vgq, 1vgr – OfFCT (mutant) + CoA
1t4c – OfFCT + oxalyl-aspartyl anhydride + CoA
2vjm – OfFCT + aspartyl-formyl anhydride + CoA
2vjo – OfFCT (mutant) + oxalate + CoA
References
- ↑ Ricagno S, Jonsson S, Richards N, Lindqvist Y. Formyl-CoA transferase encloses the CoA binding site at the interface of an interlocked dimer. EMBO J. 2003 Jul 1;22(13):3210-9. PMID:12839984 doi:http://dx.doi.org/10.1093/emboj/cdg333
- ↑ Berthold CL, Toyota CG, Richards NG, Lindqvist Y. Reinvestigation of the catalytic mechanism of formyl-CoA transferase, a class III CoA-transferase. J Biol Chem. 2008 Mar 7;283(10):6519-29. Epub 2007 Dec 27. PMID:18162462 doi:10.1074/jbc.M709353200
