Paxillin

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*Paxillin (residues 1-20)
+
*Paxillin LD1 (residues 1-20)
**[[4edn]] – hPXN + beta-parvin CH2 domain - human<br />
**[[4edn]] – hPXN + beta-parvin CH2 domain - human<br />
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**[[4xgz]], [[4xh2]] – hPXN + antibody<br />
**[[4xgz]], [[4xh2]] – hPXN + antibody<br />
**[[1ow8]], [[1ow7]] – hPXN + focal adhesion kinase focal adhesion targeting domain <br />
**[[1ow8]], [[1ow7]] – hPXN + focal adhesion kinase focal adhesion targeting domain <br />
 +
**[[5w93]] – PXN + P130CAS - mouse<br />
 +
 +
*Paxillin LD4 (residues 20-41)
 +
 +
**[[6iui]] – hPXN + GIT1 PBD domain<br />
*Paxillin (residues 139-162)
*Paxillin (residues 139-162)
Line 40: Line 45:
**[[2o9v]] – hPXN + ponsin SH3 domain<br />
**[[2o9v]] – hPXN + ponsin SH3 domain<br />
 +
 +
*Paxillin LIM4 domain (residues 527-591)
 +
 +
**[[6u4m]] – hPXN - NMR<br />
 +
**[[6u4n]] – hPXN + kindling-2 - NMR<br />
}}
}}

Revision as of 09:43, 13 November 2019

Human paxillin LD4 domain complex (blue) with α-parvin (green), tetraethylene glycol, triethylene glycol and etylene glycol (PDB code 2vzi)

Drag the structure with the mouse to rotate

3D structures of paxillin

Updated on 13-November-2019

References

  1. Tumbarello DA, Brown MC, Turner CE. The paxillin LD motifs. FEBS Lett. 2002 Feb 20;513(1):114-8. PMID:11911889
  2. Jagadeeswaran R, Surawska H, Krishnaswamy S, Janamanchi V, Mackinnon AC, Seiwert TY, Loganathan S, Kanteti R, Reichman T, Nallasura V, Schwartz S, Faoro L, Wang YC, Girard L, Tretiakova MS, Ahmed S, Zumba O, Soulii L, Bindokas VP, Szeto LL, Gordon GJ, Bueno R, Sugarbaker D, Lingen MW, Sattler M, Krausz T, Vigneswaran W, Natarajan V, Minna J, Vokes EE, Ferguson MK, Husain AN, Salgia R. Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Cancer Res. 2008 Jan 1;68(1):132-42. doi: 10.1158/0008-5472.CAN-07-1998. PMID:18172305 doi:http://dx.doi.org/10.1158/0008-5472.CAN-07-1998

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Michal Harel, Alexander Berchansky

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