6ens
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of mouse wild-type RKIP== | |
| - | + | <StructureSection load='6ens' size='340' side='right' caption='[[6ens]], [[Resolution|resolution]] 1.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ens]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ENS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ENS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ens FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ens OCA], [http://pdbe.org/6ens PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ens RCSB], [http://www.ebi.ac.uk/pdbsum/6ens PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ens ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PEBP1_MOUSE PEBP1_MOUSE]] Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation (By similarity). HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hirschbeck, M]] | ||
| + | [[Category: Kisker, C]] | ||
| + | [[Category: Koelmel, W]] | ||
| + | [[Category: Lorenz, K]] | ||
| + | [[Category: Schindelin, H]] | ||
| + | [[Category: Pbp]] | ||
| + | [[Category: Pebp]] | ||
| + | [[Category: Rkip]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 07:05, 13 December 2017
Structure of mouse wild-type RKIP
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Categories: Hirschbeck, M | Kisker, C | Koelmel, W | Lorenz, K | Schindelin, H | Pbp | Pebp | Rkip | Signaling protein
