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3f6e
From Proteopedia
(Difference between revisions)
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==Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor 3-PKB== | ==Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor 3-PKB== | ||
| - | <StructureSection load='3f6e' size='340' side='right' caption='[[3f6e]], [[Resolution|resolution]] 1.34Å' scene=''> | + | <StructureSection load='3f6e' size='340' side='right'caption='[[3f6e]], [[Resolution|resolution]] 1.34Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3f6e]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3f6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_fluorescens_putidus"_flugge_1886 "bacillus fluorescens putidus" flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F6E FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8PA:3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-[(1S,2E)-1-HYDROXY-3-PYRIDIN-3-YLPROP-2-EN-1-YL]-4-METHYL-1,3-THIAZOL-3-IUM'>8PA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8PA:3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-[(1S,2E)-1-HYDROXY-3-PYRIDIN-3-YLPROP-2-EN-1-YL]-4-METHYL-1,3-THIAZOL-3-IUM'>8PA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3f6b|3f6b]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3f6b|3f6b]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mdlC ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mdlC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=303 "Bacillus fluorescens putidus" Flugge 1886])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Benzoylformate_decarboxylase Benzoylformate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.7 4.1.1.7] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f6e OCA], [https://pdbe.org/3f6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f6e RCSB], [https://www.ebi.ac.uk/pdbsum/3f6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f6e ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/3f6e_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/3f6e_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Bacillus fluorescens putidus flugge 1886]] | [[Category: Bacillus fluorescens putidus flugge 1886]] | ||
[[Category: Benzoylformate decarboxylase]] | [[Category: Benzoylformate decarboxylase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Brandt, G S]] | [[Category: Brandt, G S]] | ||
[[Category: Jordan, F]] | [[Category: Jordan, F]] | ||
Revision as of 09:24, 23 February 2022
Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor 3-PKB
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Categories: Bacillus fluorescens putidus flugge 1886 | Benzoylformate decarboxylase | Large Structures | Brandt, G S | Jordan, F | Kenyon, G L | McLeish, M J | Petsko, G A | Ringe, D | Aromatic hydrocarbons catabolism | Calcium | Decarboxylase | Lyase | Magnesium | Mandelate pathway | Metal-binding | Thiamin adduct | Thiamine pyrophosphate
