This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5yjl
From Proteopedia
(Difference between revisions)
m (Protected "5yjl" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with NADPH and GBP== | |
| - | + | <StructureSection load='5yjl' size='340' side='right' caption='[[5yjl]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yjl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YJL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YJL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamyl-tRNA_reductase Glutamyl-tRNA reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.70 1.2.1.70] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yjl OCA], [http://pdbe.org/5yjl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yjl RCSB], [http://www.ebi.ac.uk/pdbsum/5yjl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yjl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HEM11_ARATH HEM11_ARATH]] Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). Probably involved in the tetrapyrrole synthesis required for the chlorophyll biosynthesis.<ref>PMID:7908550</ref> <ref>PMID:12139011</ref> [[http://www.uniprot.org/uniprot/GLUBP_ARATH GLUBP_ARATH]] Involved in the regulation of glutamyl-tRNA reductase (GluTR) which is important for the synthesis and distribution of 5-aminolevulinate, a precursor in heme and chlorophyll biosynthesis (PubMed:22180625). Stimulates GluTR activity and regulates glutamate-1-semialdehyde release. May play a role in heme metabolism (PubMed:24753615). Necessary for efficient photosynthetic electron transport in chloroplasts (PubMed:20657737). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Glutamyl-tRNA reductase]] | ||
| + | [[Category: Feng, H]] | ||
| + | [[Category: Zhao, A]] | ||
| + | [[Category: Ala]] | ||
| + | [[Category: Gtr]] | ||
| + | [[Category: Photosynthesis]] | ||
| + | [[Category: Tetrapyrrole]] | ||
Revision as of 05:29, 30 May 2018
Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with NADPH and GBP
| |||||||||||
Categories: Glutamyl-tRNA reductase | Feng, H | Zhao, A | Ala | Gtr | Photosynthesis | Tetrapyrrole
