1zih

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1zih.gif|left|200px]]
[[Image:1zih.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1zih |SIZE=350|CAPTION= <scene name='initialview01'>1zih</scene>
+
The line below this paragraph, containing "STRUCTURE_1zih", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1zih| PDB=1zih | SCENE= }}
-
|RELATEDENTRY=[[1zif|1ZIF]], [[1zig|1ZIG]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zih OCA], [http://www.ebi.ac.uk/pdbsum/1zih PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1zih RCSB]</span>
+
-
}}
+
'''GCAA RNA TETRALOOP, NMR, 10 STRUCTURES'''
'''GCAA RNA TETRALOOP, NMR, 10 STRUCTURES'''
Line 19: Line 16:
==About this Structure==
==About this Structure==
-
1ZIH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZIH OCA].
+
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZIH OCA].
==Reference==
==Reference==
A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9000624 9000624]
A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9000624 9000624]
-
[[Category: Protein complex]]
 
[[Category: Heus, H A.]]
[[Category: Heus, H A.]]
[[Category: Jucker, F M.]]
[[Category: Jucker, F M.]]
Line 29: Line 25:
[[Category: Pardi, A.]]
[[Category: Pardi, A.]]
[[Category: Yip, P F.]]
[[Category: Yip, P F.]]
-
[[Category: gnra]]
+
[[Category: Gnra]]
-
[[Category: hairpin]]
+
[[Category: Hairpin]]
-
[[Category: ribonucleic acid]]
+
[[Category: Ribonucleic acid]]
-
[[Category: rna]]
+
[[Category: Rna]]
-
[[Category: tetraloop]]
+
[[Category: Tetraloop]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 17:40:00 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:37:04 2008''
+

Revision as of 14:40, 3 May 2008

Image:1zih.gif

Template:STRUCTURE 1zih

GCAA RNA TETRALOOP, NMR, 10 STRUCTURES


Overview

RNA hairpin loops containing a GNRA consensus sequence are the most frequently occurring hairpins in a variety of prokaryotic and eukaryotic RNAs. These tetraloops play important functional roles in RNA folding, in RNA-RNA tertiary interactions and as protein binding sites. Homo and heteronuclear NMR spectroscopy have been used to determine the structures of the most abundant members of the GNRA tetraloop family: the GAGA, GCAA and GAAA loops closed by a C-G base pair. Analysis of the structures of these three hairpin loops reveals a network of heterogeneous hydrogen bonds. The loops contain a G-A base pair, a G base-phosphate hydrogen bond and several 2' OH-base hydrogen bonds. These intramolecular interactions and the extensive base stacking in the loop help explain the high thermodynamic stability and give insight into the diverse biological roles of the GNRA RNA hairpins.

About this Structure

Full crystallographic information is available from OCA.

Reference

A network of heterogeneous hydrogen bonds in GNRA tetraloops., Jucker FM, Heus HA, Yip PF, Moors EH, Pardi A, J Mol Biol. 1996 Dec 20;264(5):968-80. PMID:9000624 Page seeded by OCA on Sat May 3 17:40:00 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1zih"
Personal tools