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3fd4
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Epstein-Barr virus gp42 protein== | ==Crystal Structure of Epstein-Barr virus gp42 protein== | ||
| - | <StructureSection load='3fd4' size='340' side='right' caption='[[3fd4]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='3fd4' size='340' side='right'caption='[[3fd4]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fd4]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fd4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ebvb9 Ebvb9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FD4 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BZLF2 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BZLF2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10377 EBVB9])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fd4 OCA], [https://pdbe.org/3fd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fd4 RCSB], [https://www.ebi.ac.uk/pdbsum/3fd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fd4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/GP42_EBVB9 GP42_EBVB9]] Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells.<ref>PMID:12042810</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/3fd4_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/3fd4_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Ebvb9]] | [[Category: Ebvb9]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Jardetzky, T]] | [[Category: Jardetzky, T]] | ||
[[Category: Kirschner, A]] | [[Category: Kirschner, A]] | ||
Revision as of 07:58, 2 March 2022
Crystal Structure of Epstein-Barr virus gp42 protein
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