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3ie0
From Proteopedia
(Difference between revisions)
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==Crystal Structure of S378Y mutant TTHA0252 from Thermus thermophilus HB8== | ==Crystal Structure of S378Y mutant TTHA0252 from Thermus thermophilus HB8== | ||
| - | <StructureSection load='3ie0' size='340' side='right' caption='[[3ie0]], [[Resolution|resolution]] 2.73Å' scene=''> | + | <StructureSection load='3ie0' size='340' side='right'caption='[[3ie0]], [[Resolution|resolution]] 2.73Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ie0]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ie0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2zdd 2zdd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IE0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IE0 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dkf|2dkf]], [[3a4y|3a4y]], [[3idz|3idz]], [[3ie1|3ie1]], [[3ie2|3ie2]], [[3iek|3iek]], [[3iel|3iel]], [[3iem|3iem]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dkf|2dkf]], [[3a4y|3a4y]], [[3idz|3idz]], [[3ie1|3ie1]], [[3ie2|3ie2]], [[3iek|3iek]], [[3iel|3iel]], [[3iem|3iem]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0252 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0252 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ie0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ie0 OCA], [https://pdbe.org/3ie0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ie0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ie0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ie0 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/RNSE_THET8 RNSE_THET8]] Has endoribonuclease activity towards 23S and 16S rRNA (in vitro). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ie0_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/3ie0_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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==See Also== | ==See Also== | ||
| - | *[[ | + | *[[Ribonuclease 3D structures|Ribonuclease 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thet8]] | [[Category: Thet8]] | ||
[[Category: Ishikawa, H]] | [[Category: Ishikawa, H]] | ||
Revision as of 07:46, 10 November 2021
Crystal Structure of S378Y mutant TTHA0252 from Thermus thermophilus HB8
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Categories: Large Structures | Thet8 | Ishikawa, H | Kuramitsu, S | Masui, R | Nakagawa, N | Structural genomic | Yokoyama, S | Endonuclease | Hydrolase | Metal-binding | Metallo beta lactamase fold | National project on protein structural and functional analyse | Nppsfa | Nuclease | Rna-binding | Rrna processing | Rsgi
