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3jxd

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Current revision (08:05, 6 September 2023) (edit) (undo)
 
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==Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9C in the presence of Rb+==
==Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9C in the presence of Rb+==
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<StructureSection load='3jxd' size='340' side='right' caption='[[3jxd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3jxd' size='340' side='right'caption='[[3jxd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3jxd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpp22 Bpp22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JXD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JXD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3jxd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JXD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RB:RUBIDIUM+ION'>RB</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jxb|3jxb]], [[3jxc|3jxc]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RB:RUBIDIUM+ION'>RB</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10754 BPP22])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jxd OCA], [https://pdbe.org/3jxd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jxd RCSB], [https://www.ebi.ac.uk/pdbsum/3jxd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jxd ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jxd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jxd OCA], [http://pdbe.org/3jxd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jxd RCSB], [http://www.ebi.ac.uk/pdbsum/3jxd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jxd ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RPC2_BPP22 RPC2_BPP22]] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
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[https://www.uniprot.org/uniprot/RPC2_BPP22 RPC2_BPP22] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/3jxd_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jx/3jxd_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpp22]]
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[[Category: Large Structures]]
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[[Category: Koudelka, G B]]
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[[Category: Salmonella virus P22]]
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[[Category: Watkins, D]]
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[[Category: Koudelka GB]]
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[[Category: Williams, L D]]
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[[Category: Watkins D]]
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[[Category: Dna-binding]]
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[[Category: Williams LD]]
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[[Category: Protein-dna complex]]
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[[Category: Repressor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transcription regulator]]
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Current revision

Crystal structure of the P22 c2 repressor protein in complex with synthetic operator 9C in the presence of Rb+

PDB ID 3jxd

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