3kvo

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Current revision (08:25, 6 September 2023) (edit) (undo)
 
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==Crystal structure of the catalytic domain of human Hydroxysteroid dehydrogenase like 2 (HSDL2)==
==Crystal structure of the catalytic domain of human Hydroxysteroid dehydrogenase like 2 (HSDL2)==
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<StructureSection load='3kvo' size='340' side='right' caption='[[3kvo]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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<StructureSection load='3kvo' size='340' side='right'caption='[[3kvo]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kvo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KVO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KVO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kvo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KVO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KVO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3e03|3e03]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSDL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kvo OCA], [https://pdbe.org/3kvo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kvo RCSB], [https://www.ebi.ac.uk/pdbsum/3kvo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kvo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kvo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kvo OCA], [http://pdbe.org/3kvo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kvo RCSB], [http://www.ebi.ac.uk/pdbsum/3kvo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kvo ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HSDL2_HUMAN HSDL2_HUMAN]] Has apparently no steroid dehydrogenase activity.<ref>PMID:19703561</ref>
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[https://www.uniprot.org/uniprot/HSDL2_HUMAN HSDL2_HUMAN] Has apparently no steroid dehydrogenase activity.<ref>PMID:19703561</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/3kvo_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kv/3kvo_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H]]
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[[Category: Large Structures]]
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[[Category: Bhatia, C]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bhatia C]]
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[[Category: Delft, F von]]
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[[Category: Bountra C]]
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[[Category: Edwards, A]]
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[[Category: Edwards A]]
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[[Category: Huang, J]]
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[[Category: Huang J]]
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[[Category: Kavanagh, K L]]
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[[Category: Kavanagh KL]]
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[[Category: Krojer, T]]
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[[Category: Krojer T]]
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[[Category: Muniz, J R.C]]
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[[Category: Muniz JRC]]
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[[Category: Oppermann, U]]
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[[Category: Oppermann U]]
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[[Category: Pike, A C.W]]
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[[Category: Pike ACW]]
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[[Category: Pilka, E]]
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[[Category: Pilka E]]
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[[Category: Structural genomic]]
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[[Category: Ugochukwu E]]
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[[Category: Ugochukwu, E]]
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[[Category: Verdin EM]]
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[[Category: Verdin, E M]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Von Delft F]]
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[[Category: Hsdl2]]
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[[Category: Human hydroxysteroid dehydrogenase like 2]]
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[[Category: Nad]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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[[Category: Peroxisome]]
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[[Category: Sdhl2]]
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[[Category: Sgc]]
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Current revision

Crystal structure of the catalytic domain of human Hydroxysteroid dehydrogenase like 2 (HSDL2)

PDB ID 3kvo

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