3kzw

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==Crystal structure of cytosol aminopeptidase from Staphylococcus aureus COL==
==Crystal structure of cytosol aminopeptidase from Staphylococcus aureus COL==
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<StructureSection load='3kzw' size='340' side='right' caption='[[3kzw]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='3kzw' size='340' side='right'caption='[[3kzw]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3kzw]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KZW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KZW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3kzw]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_COL Staphylococcus aureus subsp. aureus COL]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KZW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KZW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SACOL0945 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Leucyl_aminopeptidase Leucyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.1 3.4.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kzw OCA], [https://pdbe.org/3kzw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kzw RCSB], [https://www.ebi.ac.uk/pdbsum/3kzw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kzw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3kzw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kzw OCA], [http://pdbe.org/3kzw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3kzw RCSB], [http://www.ebi.ac.uk/pdbsum/3kzw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3kzw ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q5HHE3_STAAC Q5HHE3_STAAC]] Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).[SAAS:SAAS008283_004_018866]
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[https://www.uniprot.org/uniprot/A0A0H2WYH0_STAAC A0A0H2WYH0_STAAC]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/3kzw_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/3kzw_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kzw ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kzw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Leucyl aminopeptidase]]
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[[Category: Large Structures]]
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[[Category: Staac]]
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[[Category: Staphylococcus aureus subsp. aureus COL]]
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[[Category: Structural genomic]]
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[[Category: Dubrovska I]]
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[[Category: Dubrovska, I]]
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[[Category: Halavaty A]]
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[[Category: Halavaty, A]]
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[[Category: Hattne J]]
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[[Category: Hattne, J]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Otwinowski Z]]
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[[Category: Otwinowski, Z]]
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[[Category: Scott P]]
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[[Category: Scott, P]]
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[[Category: Shuvalova L]]
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[[Category: Shuvalova, L]]
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[[Category: Winsor J]]
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[[Category: Winsor, J]]
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[[Category: Aminopeptidase]]
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[[Category: Csgid]]
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[[Category: Cytosol aminopeptidase]]
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[[Category: Hydrolase]]
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[[Category: Manganese]]
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[[Category: Metal-binding]]
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[[Category: Protease]]
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Current revision

Crystal structure of cytosol aminopeptidase from Staphylococcus aureus COL

PDB ID 3kzw

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