3l92

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Current revision (08:32, 6 September 2023) (edit) (undo)
 
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==Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.==
==Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.==
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<StructureSection load='3l92' size='340' side='right' caption='[[3l92]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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<StructureSection load='3l92' size='340' side='right'caption='[[3l92]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3l92]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L92 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3l92]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L92 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">coaD, kdtB, y0088, YPO0053, YP_0054 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantetheine-phosphate_adenylyltransferase Pantetheine-phosphate adenylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.3 2.7.7.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l92 OCA], [https://pdbe.org/3l92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l92 RCSB], [https://www.ebi.ac.uk/pdbsum/3l92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l92 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l92 OCA], [http://pdbe.org/3l92 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l92 RCSB], [http://www.ebi.ac.uk/pdbsum/3l92 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l92 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/COAD_YERPE COAD_YERPE]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
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[https://www.uniprot.org/uniprot/COAD_YERPE COAD_YERPE] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/3l92_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/3l92_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pantetheine-phosphate adenylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Yersinia pestis co92]]
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[[Category: Yersinia pestis CO92]]
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[[Category: Anderson, W F]]
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[[Category: Anderson WF]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A]]
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[[Category: Kwon K]]
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[[Category: Kwon, K]]
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[[Category: Makowska-grzyska M]]
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[[Category: Makowska-grzyska, M]]
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[[Category: Maltseva N]]
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[[Category: Maltseva, N]]
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[[Category: Osipiuk J]]
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[[Category: Osipiuk, J]]
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[[Category: Atp-binding]]
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[[Category: Coenzyme some]]
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[[Category: Coenzyme a biosynthesis]]
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[[Category: Csgid]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Phosphopantetheine adenylyltransferase]]
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[[Category: Transferase]]
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Current revision

Phosphopantetheine adenylyltransferase from Yersinia pestis complexed with coenzyme A.

PDB ID 3l92

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