1ztj

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[[Image:1ztj.gif|left|200px]]
[[Image:1ztj.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1ztj |SIZE=350|CAPTION= <scene name='initialview01'>1ztj</scene>, resolution 2.05&Aring;
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The line below this paragraph, containing "STRUCTURE_1ztj", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=632:2-(5-BENZYLAMINO-2-METHYLSULFANYL-6-OXO-6H-PYRIMIDIN-1-YL)-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-ACETAMIDE'>632</scene>, <scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_XIa Coagulation factor XIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.27 3.4.21.27] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= F11 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_1ztj| PDB=1ztj | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ztj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ztj OCA], [http://www.ebi.ac.uk/pdbsum/1ztj PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ztj RCSB]</span>
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}}
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'''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide'''
'''Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide'''
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[[Category: Rynkiewicz, M.]]
[[Category: Rynkiewicz, M.]]
[[Category: Strickler, J E.]]
[[Category: Strickler, J E.]]
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[[Category: fxia]]
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[[Category: Fxia]]
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[[Category: inhibitor]]
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[[Category: Inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:03:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:41:28 2008''
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Revision as of 15:03, 3 May 2008

Template:STRUCTURE 1ztj

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Benzylamino-2-methylsulfanyl-6-oxo-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide


Disease

Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]

About this Structure

1ZTJ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA. Page seeded by OCA on Sat May 3 18:03:15 2008

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OCA

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