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1nve

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==Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ and NAD==
==Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ and NAD==
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<StructureSection load='1nve' size='340' side='right' caption='[[1nve]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
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<StructureSection load='1nve' size='340' side='right'caption='[[1nve]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1nve]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/A._nidulans A. nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NVE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1nve]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/A._nidulans A. nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1NVE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nr5|1nr5]], [[1nrx|1nrx]], [[1nvd|1nvd]], [[1nvb|1nvb]], [[1nua|1nua]], [[1nva|1nva]], [[1nvf|1nvf]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nr5|1nr5]], [[1nrx|1nrx]], [[1nvd|1nvd]], [[1nvb|1nvb]], [[1nua|1nua]], [[1nva|1nva]], [[1nvf|1nvf]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AROMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 A. nidulans])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AROMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=162425 A. nidulans])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_synthase 3-dehydroquinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.4 4.2.3.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nve OCA], [http://pdbe.org/1nve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nve RCSB], [http://www.ebi.ac.uk/pdbsum/1nve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nve ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1nve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nve OCA], [http://pdbe.org/1nve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nve RCSB], [http://www.ebi.ac.uk/pdbsum/1nve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nve ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/1nve_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/1nve_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: 3-dehydroquinate synthase]]
[[Category: 3-dehydroquinate synthase]]
[[Category: A. nidulans]]
[[Category: A. nidulans]]
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[[Category: Large Structures]]
[[Category: Hawkins, A R]]
[[Category: Hawkins, A R]]
[[Category: Lamb, H K]]
[[Category: Lamb, H K]]

Revision as of 08:57, 2 December 2020

Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ and NAD

PDB ID 1nve

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