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4wc2

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==Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog==
==Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog==
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<StructureSection load='4wc2' size='340' side='right' caption='[[4wc2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4wc2' size='340' side='right'caption='[[4wc2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wc2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WC2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WC2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wc2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5] and [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WC2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vfg|1vfg]], [[4wby|4wby]], [[4wbz|4wbz]], [[4wc0|4wc0]], [[4wc1|4wc1]], [[4wc3|4wc3]], [[4wc4|4wc4]], [[4wc5|4wc5]], [[4wc6|4wc6]], [[4wc7|4wc7]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wc2 OCA], [https://pdbe.org/4wc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wc2 RCSB], [https://www.ebi.ac.uk/pdbsum/4wc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wc2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pcnB1, aq_411 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wc2 OCA], [http://pdbe.org/4wc2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wc2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wc2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wc2 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AATNT_AQUAE AATNT_AQUAE] tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the terminal adenosine residue to tRNA (PubMed:11701927, PubMed:25914059). Can incorporate CMP into tRNA ending with C74C75 (tRNACC), with very weak efficiency (PubMed:25914059).<ref>PMID:11701927</ref> <ref>PMID:25914059</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4wc2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4wc2" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Poly(A) Polymerase|Poly(A) Polymerase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aquae]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Tomita, K]]
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[[Category: Large Structures]]
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[[Category: Yamashita, S]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: A-adding enzyme]]
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[[Category: Tomita K]]
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[[Category: Cca-adding enzyme]]
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[[Category: Yamashita S]]
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[[Category: Rna nucleotidyltransferase]]
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[[Category: Transferase-rna complex]]
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Revision as of 07:01, 7 April 2023

Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog

PDB ID 4wc2

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