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4yv8
From Proteopedia
(Difference between revisions)
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==Crystal structure of cathepsin K bound to the covalent inhibitor lichostatinal== | ==Crystal structure of cathepsin K bound to the covalent inhibitor lichostatinal== | ||
| - | <StructureSection load='4yv8' size='340' side='right' caption='[[4yv8]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4yv8' size='340' side='right'caption='[[4yv8]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4yv8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Actinomycete_095-35 Actinomycete 095-35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YV8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YV8 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4yv8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Actinomycete_095-35 Actinomycete 095-35]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YV8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YV8 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AG2:AGMATINE'>AG2</scene>, <scene name='pdbligand=RGL:ARGINAL'>RGL</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AG2:AGMATINE'>AG2</scene>, <scene name='pdbligand=RGL:ARGINAL'>RGL</scene>, <scene name='pdbligand=URE:UREA'>URE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yva|4yva]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yva|4yva]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSK, CTSO, CTSO2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yv8 OCA], [http://pdbe.org/4yv8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yv8 RCSB], [http://www.ebi.ac.uk/pdbsum/4yv8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yv8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yv8 OCA], [http://pdbe.org/4yv8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yv8 RCSB], [http://www.ebi.ac.uk/pdbsum/4yv8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yv8 ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4yv8" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4yv8" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Actinomycete 095-35]] | [[Category: Actinomycete 095-35]] | ||
[[Category: Cathepsin K]] | [[Category: Cathepsin K]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Aguda, A H]] | [[Category: Aguda, A H]] | ||
[[Category: Brayer, G D]] | [[Category: Brayer, G D]] | ||
Revision as of 08:00, 21 May 2019
Crystal structure of cathepsin K bound to the covalent inhibitor lichostatinal
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