200d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:200d.gif|left|200px]]
[[Image:200d.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 200d |SIZE=350|CAPTION= <scene name='initialview01'>200d</scene>, resolution 1.850&Aring;
+
The line below this paragraph, containing "STRUCTURE_200d", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_200d| PDB=200d | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=200d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=200d OCA], [http://www.ebi.ac.uk/pdbsum/200d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=200d RCSB]</span>
+
-
}}
+
'''STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE'''
'''STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE'''
Line 19: Line 16:
==About this Structure==
==About this Structure==
-
200D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=200D OCA].
+
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=200D OCA].
==Reference==
==Reference==
Stable loop in the crystal structure of the intercalated four-stranded cytosine-rich metazoan telomere., Kang C, Berger I, Lockshin C, Ratliff R, Moyzis R, Rich A, Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3874-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7731999 7731999]
Stable loop in the crystal structure of the intercalated four-stranded cytosine-rich metazoan telomere., Kang C, Berger I, Lockshin C, Ratliff R, Moyzis R, Rich A, Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3874-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7731999 7731999]
-
[[Category: Protein complex]]
 
[[Category: Berger, I.]]
[[Category: Berger, I.]]
[[Category: Kang, C.]]
[[Category: Kang, C.]]
Line 30: Line 26:
[[Category: Ratliff, R.]]
[[Category: Ratliff, R.]]
[[Category: Rich, A.]]
[[Category: Rich, A.]]
-
[[Category: base intercalated]]
+
[[Category: Base intercalated]]
-
[[Category: loop]]
+
[[Category: Loop]]
-
[[Category: quadruple helix]]
+
[[Category: Quadruple helix]]
-
[[Category: tetraplex]]
+
[[Category: Tetraplex]]
-
[[Category: u-dna]]
+
[[Category: U-dna]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:17:32 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:44:01 2008''
+

Revision as of 15:17, 3 May 2008

Image:200d.gif

Template:STRUCTURE 200d

STABLE LOOP IN THE CRYSTAL STRUCTURE OF THE INTERCALATED FOUR-STRANDED CYTOSINE-RICH METAZOAN TELOMERE


Overview

In most metazoans, the telomeric cytosine-rich strand repeating sequence is d(TAACCC). The crystal structure of this sequence was solved to 1.9-A resolution. Four strands associate via the cytosine-containing parts to form a four-stranded intercalated structure held together by C.C+ hydrogen bonds. The base-paired strands are parallel to each other, and the two duplexes are intercalated into each other in opposite orientations. One TAA end forms a highly stabilized loop with the 5' thymine Hoogsteen-base-paired to the third adenine. The 5' end of this loop is in close proximity to the 3' end of one of the other intercalated cytosine strands. Instead of being entirely in a DNA duplex, this structure suggests the possibility of an alternative conformation for the cytosine-rich telomere strands.

About this Structure

Full crystallographic information is available from OCA.

Reference

Stable loop in the crystal structure of the intercalated four-stranded cytosine-rich metazoan telomere., Kang C, Berger I, Lockshin C, Ratliff R, Moyzis R, Rich A, Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3874-8. PMID:7731999 Page seeded by OCA on Sat May 3 18:17:32 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/200d"
Personal tools