205d

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[[Image:205d.jpg|left|200px]]
[[Image:205d.jpg|left|200px]]
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{{Structure
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|PDB= 205d |SIZE=350|CAPTION= <scene name='initialview01'>205d</scene>, resolution 2.640&Aring;
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The line below this paragraph, containing "STRUCTURE_205d", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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{{STRUCTURE_205d| PDB=205d | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=205d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=205d OCA], [http://www.ebi.ac.uk/pdbsum/205d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=205d RCSB]</span>
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'''STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP'''
'''STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP'''
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==About this Structure==
==About this Structure==
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205D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=205D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=205D OCA].
==Reference==
==Reference==
Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7719854 7719854]
Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7719854 7719854]
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[[Category: Protein complex]]
 
[[Category: Baeyens, K J.]]
[[Category: Baeyens, K J.]]
[[Category: Bondt, H L.De.]]
[[Category: Bondt, H L.De.]]
[[Category: Holbrook, S R.]]
[[Category: Holbrook, S R.]]
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[[Category: a-rna]]
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[[Category: A-rna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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[[Category: internal loop]]
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[[Category: Internal loop]]
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[[Category: mismatched]]
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[[Category: Mismatched]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:17:54 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:44:06 2008''
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Revision as of 15:17, 3 May 2008

Image:205d.jpg

Template:STRUCTURE 205d

STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP


Overview

The crystal structure of the RNA dodecamer 5'-GGACUUUGGUCC-3' has been determined from X-ray diffraction data to 2.6 A resolution. This oligomer forms an asymmetric double helix in the crystal. Four consecutive non-Watson-Crick base-pairs are formed in the middle of the duplex including the first intrahelical U-U (or T-T) pairs observed in an oligonucleotide crystal structure. Two different conformations of U-U pairs are observed in the context of the surrounding sequence. One of these pairs is highly twisted, allowing a bound water to bridge across strands in the major groove. The crystal packing illustrates a new form of RNA helix-helix interaction.

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:7719854 Page seeded by OCA on Sat May 3 18:17:54 2008

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OCA

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