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5jqj
From Proteopedia
(Difference between revisions)
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==Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-1== | ==Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-1== | ||
| - | <StructureSection load='5jqj' size='340' side='right' caption='[[5jqj]], [[Resolution|resolution]] 1.67Å' scene=''> | + | <StructureSection load='5jqj' size='340' side='right'caption='[[5jqj]], [[Resolution|resolution]] 1.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5jqj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5jqj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JQJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jqj OCA], [https://pdbe.org/5jqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jqj RCSB], [https://www.ebi.ac.uk/pdbsum/5jqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jqj ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. |
| + | |||
| + | ==See Also== | ||
| + | *[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Klebsiella pneumoniae]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Carr PD]] |
| - | [[Category: | + | [[Category: Hong N-S]] |
| - | + | [[Category: Jackson CJ]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[Category: | + | |
Current revision
Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-1
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