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5lod

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Current revision (18:37, 18 October 2023) (edit) (undo)
 
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==Crystal structure of HhaI DNA methyltransferase in APO form==
==Crystal structure of HhaI DNA methyltransferase in APO form==
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<StructureSection load='5lod' size='340' side='right' caption='[[5lod]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='5lod' size='340' side='right'caption='[[5lod]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5lod]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_10014 Atcc 10014]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LOD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5lod]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_parahaemolyticus Haemophilus parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LOD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hhaIM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=735 ATCC 10014])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_(cytosine-5-)-methyltransferase DNA (cytosine-5-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.37 2.1.1.37] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lod OCA], [https://pdbe.org/5lod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lod RCSB], [https://www.ebi.ac.uk/pdbsum/5lod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lod ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lod OCA], [http://pdbe.org/5lod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lod RCSB], [http://www.ebi.ac.uk/pdbsum/5lod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lod ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
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[https://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5lod" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5lod" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 10014]]
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[[Category: Haemophilus parahaemolyticus]]
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[[Category: Rondelet, G]]
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[[Category: Large Structures]]
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[[Category: Wouters, J]]
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[[Category: Rondelet G]]
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[[Category: Apo form]]
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[[Category: Wouters J]]
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[[Category: C5-methylcytosine]]
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[[Category: Dna methyltransferase]]
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[[Category: M hhai]]
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[[Category: Transferase]]
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Current revision

Crystal structure of HhaI DNA methyltransferase in APO form

PDB ID 5lod

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