241d
From Proteopedia
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[[Image:241d.gif|left|200px]] | [[Image:241d.gif|left|200px]] | ||
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| - | + | {{STRUCTURE_241d| PDB=241d | SCENE= }} | |
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'''EXTENSION OF THE FOUR-STRANDED INTERCALATED CYTOSINE MOTIF BY ADENINE.ADENINE BASE PAIRING IN THE CRYSTAL STRUCTURE OF D(CCCAAT)''' | '''EXTENSION OF THE FOUR-STRANDED INTERCALATED CYTOSINE MOTIF BY ADENINE.ADENINE BASE PAIRING IN THE CRYSTAL STRUCTURE OF D(CCCAAT)''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=241D OCA]. | |
==Reference== | ==Reference== | ||
Extension of the four-stranded intercalated cytosine motif by adenine.adenine base pairing in the crystal structure of d(CCCAAT)., Berger I, Kang C, Fredian A, Ratliff R, Moyzis R, Rich A, Nat Struct Biol. 1995 May;2(5):416-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7664099 7664099] | Extension of the four-stranded intercalated cytosine motif by adenine.adenine base pairing in the crystal structure of d(CCCAAT)., Berger I, Kang C, Fredian A, Ratliff R, Moyzis R, Rich A, Nat Struct Biol. 1995 May;2(5):416-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7664099 7664099] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Berger, I.]] | [[Category: Berger, I.]] | ||
[[Category: Fredian, A.]] | [[Category: Fredian, A.]] | ||
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[[Category: Ratliff, R.]] | [[Category: Ratliff, R.]] | ||
[[Category: Rich, A.]] | [[Category: Rich, A.]] | ||
| - | [[Category: | + | [[Category: Arallel-stranded tetraplex]] |
| - | [[Category: | + | [[Category: Base intercalated]] |
| - | [[Category: | + | [[Category: Mismatched]] |
| - | [[Category: | + | [[Category: Quadruple helix]] |
| - | [[Category: | + | [[Category: U-dna]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:22:08 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 15:22, 3 May 2008
EXTENSION OF THE FOUR-STRANDED INTERCALATED CYTOSINE MOTIF BY ADENINE.ADENINE BASE PAIRING IN THE CRYSTAL STRUCTURE OF D(CCCAAT)
Overview
The crystal structure of d(CCCAAT), refined at 2.0 A resolution, shows a four stranded molecule in which two parallel duplexes intercalate with opposite polarity, using cytosine.protonated cytosine base pairs. The intercalation motif in this structure is extended by adenine.adenine base pairs. Two topologically distinct broad grooves are found in the lath-like central part of the molecule with the phosphate groups on one side bent over towards each other, stabilized by bridging water molecules. At the 3' ends, two arrangements of intermolecular A.A.T base triplets are found, involving both asymmetric and symmetric A.A base pairs joined to thymine residues by Watson-Crick and reverse Hoogsteen base pairing, respectively.
About this Structure
Full crystallographic information is available from OCA.
Reference
Extension of the four-stranded intercalated cytosine motif by adenine.adenine base pairing in the crystal structure of d(CCCAAT)., Berger I, Kang C, Fredian A, Ratliff R, Moyzis R, Rich A, Nat Struct Biol. 1995 May;2(5):416-25. PMID:7664099 Page seeded by OCA on Sat May 3 18:22:08 2008
