272d

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[[Image:272d.jpg|left|200px]]
[[Image:272d.jpg|left|200px]]
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{{Structure
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|PDB= 272d |SIZE=350|CAPTION= <scene name='initialview01'>272d</scene>, resolution 2.000&Aring;
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The line below this paragraph, containing "STRUCTURE_272d", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_272d| PDB=272d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=272d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=272d OCA], [http://www.ebi.ac.uk/pdbsum/272d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=272d RCSB]</span>
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}}
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'''PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE'''
'''PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE'''
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==About this Structure==
==About this Structure==
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272D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA].
==Reference==
==Reference==
Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8781231 8781231]
Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8781231 8781231]
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[[Category: Protein complex]]
 
[[Category: Dautant, A.]]
[[Category: Dautant, A.]]
[[Category: Gallois, B.]]
[[Category: Gallois, B.]]
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[[Category: Precigoux, G.]]
[[Category: Precigoux, G.]]
[[Category: Vlieghe, D.]]
[[Category: Vlieghe, D.]]
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[[Category: b-dna]]
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[[Category: B-dna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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[[Category: intermolecular base triplet]]
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[[Category: Intermolecular base triplet]]
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[[Category: overhanging base]]
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[[Category: Overhanging base]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:24:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:45:47 2008''
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Revision as of 15:25, 3 May 2008

Image:272d.jpg

Template:STRUCTURE 272d

PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE


Overview

Nucleic acid triplexes are formed by sequence-specific interactions between single-stranded polynucleotides and the double helix. These triplexes are implicated in genetic recombination in vivo and have application to areas that include genome analysis and antigene therapy. Despite the importance of the triple helix, only limited high-resolution structural information is available. The x-ray crystal structure of the oligonucleotide d(GGCCAATTGG) is described; it was designed to contain the d(G middle dotGC)2 fragment and thus provide the basic repeat unit of a DNA triple helix. Parameters derived from this crystal structure have made it possible to construct models of both parallel and antiparallel triple helices.

About this Structure

Full crystallographic information is available from OCA.

Reference

Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure., Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O, Science. 1996 Sep 20;273(5282):1702-5. PMID:8781231 Page seeded by OCA on Sat May 3 18:24:59 2008

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