2a0b

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[[Image:2a0b.jpg|left|200px]]
[[Image:2a0b.jpg|left|200px]]
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{{Structure
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|PDB= 2a0b |SIZE=350|CAPTION= <scene name='initialview01'>2a0b</scene>, resolution 1.57&Aring;
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The line below this paragraph, containing "STRUCTURE_2a0b", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=PHB:Phosphorylation+Site'>PHB</scene> and <scene name='pdbsite=ZNB:Zn+Binding+Site'>ZNB</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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{{STRUCTURE_2a0b| PDB=2a0b | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a0b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a0b OCA], [http://www.ebi.ac.uk/pdbsum/2a0b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2a0b RCSB]</span>
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}}
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'''HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI'''
'''HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI'''
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[[Category: Mizuno, T.]]
[[Category: Mizuno, T.]]
[[Category: Shimizu, T.]]
[[Category: Shimizu, T.]]
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[[Category: four-helix bundle]]
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[[Category: Four-helix bundle]]
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[[Category: histidine kinase]]
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[[Category: Histidine kinase]]
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[[Category: phosphotransfer]]
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[[Category: Phosphotransfer]]
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[[Category: sensory transduction]]
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[[Category: Sensory transduction]]
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[[Category: two-component system]]
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[[Category: Two-component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:27:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:12 2008''
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Revision as of 15:27, 3 May 2008

Image:2a0b.jpg

Template:STRUCTURE 2a0b

HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ARCB FROM ESCHERICHIA COLI


Overview

The crystal structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor kinase ArcB from Escherichia coli has been refined to 1.57 A resolution, using the coordinates of the earlier 2.06 A structure as a starting model. The final model contained 956 protein atoms, one zinc ion and 156 water molecules, with an R factor of 19.0%. The high-resolution electron-density maps clearly revealed additional solvent molecules and seven discrete rotamers in the protein side chains. One residue, Met755, was fully buried but was able to occupy the space in the hydrophobic core by means of the two-state conformation of its side chain. One water molecule was buried in the protein core and contributed to the rigidity of the HPt domain, cooperating in the coordination of the zinc ion.

About this Structure

2A0B is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Refined structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor kinase ArcB from Escherichia coli at 1.57 A resolution., Kato M, Mizuno T, Shimizu T, Hakoshima T, Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1842-9. PMID:10531481 Page seeded by OCA on Sat May 3 18:27:00 2008

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