2a2t

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[[Image:2a2t.gif|left|200px]]
[[Image:2a2t.gif|left|200px]]
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{{Structure
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|PDB= 2a2t |SIZE=350|CAPTION= <scene name='initialview01'>2a2t</scene>, resolution 3.10&Aring;
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The line below this paragraph, containing "STRUCTURE_2a2t", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>
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{{STRUCTURE_2a2t| PDB=2a2t | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a2t OCA], [http://www.ebi.ac.uk/pdbsum/2a2t PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2a2t RCSB]</span>
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}}
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'''crystal structure of d(AAATATTT)'''
'''crystal structure of d(AAATATTT)'''
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==About this Structure==
==About this Structure==
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2A2T is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2T OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A2T OCA].
==Reference==
==Reference==
Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16301792 16301792]
Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16301792 16301792]
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[[Category: Protein complex]]
 
[[Category: Richter, M.]]
[[Category: Richter, M.]]
[[Category: Subirana, J A.]]
[[Category: Subirana, J A.]]
[[Category: Valls, N.]]
[[Category: Valls, N.]]
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[[Category: at]]
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[[Category: At]]
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[[Category: cacodylate]]
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[[Category: Cacodylate]]
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[[Category: haso]]
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[[Category: Haso]]
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[[Category: mn]]
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[[Category: Mn]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:31:56 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:47:05 2008''
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Revision as of 15:31, 3 May 2008

Image:2a2t.gif

Template:STRUCTURE 2a2t

crystal structure of d(AAATATTT)


Overview

The structure of the oligonucleotide duplex d(AAATATTT)(2) has been obtained in two crystal forms. In both cases the duplexes show Watson-Crick base pairs and are organized as a helical arrangement of stacked oligonucleotides. The helices contain either 11 duplexes in seven turns (form I) or 14 duplexes in nine turns (form II). As a result, the crystals have rather large unit cells. Such an organization of DNA duplexes has not been previously described in oligonucleotide crystal structures. The columns of stacked duplexes are organized in a pseudohexagonal arrangement. They do not show any direct lateral interactions; instead, these are indirectly mediated by shared and disordered hydrated ions. Such interactions are similar to those found in DNA fibres. The structural parameters of the individual base steps coincide with those found in other structures which contain CG terminal base pairs.

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of a DNA duplex with all-AT base pairs., Valls N, Richter M, Subirana JA, Acta Crystallogr D Biol Crystallogr. 2005 Dec;61(Pt 12):1587-93. Epub 2005, Nov 19. PMID:16301792 Page seeded by OCA on Sat May 3 18:31:56 2008

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