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3ps4
From Proteopedia
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==PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1== | ==PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1== | ||
| - | <StructureSection load='3ps4' size='340' side='right' caption='[[3ps4]], [[Resolution|resolution]] 1.85Å' scene=''> | + | <StructureSection load='3ps4' size='340' side='right'caption='[[3ps4]], [[Resolution|resolution]] 1.85Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ps4]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ps4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PS4 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAST1, KIAA0973 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAST1, KIAA0973 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ps4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ps4 OCA], [https://pdbe.org/3ps4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ps4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ps4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ps4 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/MAST1_HUMAN MAST1_HUMAN]] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity).[UniProtKB:Q9R1L5] |
| + | |||
| + | ==See Also== | ||
| + | *[[Microtubule-associated serine/threonine kinase|Microtubule-associated serine/threonine kinase]] | ||
| + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
Revision as of 08:52, 25 May 2022
PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1
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Categories: Human | Large Structures | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Cocking, R | Delft, F von | Doyle, D A | Edwards, A | Elkins, J M | Knapp, S | Krojer, T | Muniz, J R.C | Pike, A C.W | Roos, A | Structural genomic | Salah, E | Savitsky, P | Sethi, R | Ugochukwu, E | Wang, J | Weigelt, J | Kinase | Pdz domain | Serine/threonine-protein kinase | Sgc | Transferase

