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3tkp
From Proteopedia
(Difference between revisions)
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==Crystal structure of full-length human peroxiredoxin 4 in the reduced form== | ==Crystal structure of full-length human peroxiredoxin 4 in the reduced form== | ||
| - | <StructureSection load='3tkp' size='340' side='right' caption='[[3tkp]], [[Resolution|resolution]] 2.49Å' scene=''> | + | <StructureSection load='3tkp' size='340' side='right'caption='[[3tkp]], [[Resolution|resolution]] 2.49Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3tkp]] is a 5 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3tkp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TKP FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2pn8|2pn8]], [[3tkq|3tkq]], [[3tkr|3tkr]], [[3tks|3tks]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2pn8|2pn8]], [[3tkq|3tkq]], [[3tkr|3tkr]], [[3tks|3tks]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRDX4 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRDX4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tkp OCA], [https://pdbe.org/3tkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tkp RCSB], [https://www.ebi.ac.uk/pdbsum/3tkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tkp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PRDX4_HUMAN PRDX4_HUMAN]] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.<ref>PMID:9388242</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3tkp" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3tkp" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 25: | Line 28: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Peroxiredoxin]] | [[Category: Peroxiredoxin]] | ||
[[Category: Sun, F]] | [[Category: Sun, F]] | ||
Revision as of 17:02, 6 July 2022
Crystal structure of full-length human peroxiredoxin 4 in the reduced form
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Categories: Human | Large Structures | Peroxiredoxin | Sun, F | Wang, C C | Wang, L | Wang, X | Oxidoreductase | Thioredoxin fold
