5lug
From Proteopedia
(Difference between revisions)
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==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide== | ==Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide== | ||
| - | <StructureSection load='5lug' size='340' side='right' caption='[[5lug]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='5lug' size='340' side='right'caption='[[5lug]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5lug]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LUG FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2MR:N3,+N4-DIMETHYLARGININE'>2MR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lug OCA], [https://pdbe.org/5lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lug RCSB], [https://www.ebi.ac.uk/pdbsum/5lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lug ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPI2B_HUMAN SPI2B_HUMAN] Involved in the regulation of cell cycle progression, this activity is related to the inhibition of apoptosis following the removal of essential growth factors (PubMed:12145692). Exhibits H3K4me3-binding activity (PubMed:29061846).<ref>PMID:12145692</ref> <ref>PMID:29061846</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Spindlin|Spindlin]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Burgess-Brown | + | [[Category: Bountra C]] |
| - | + | [[Category: Burgess-Brown N]] | |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Gileadi | + | [[Category: Gileadi C]] |
| - | [[Category: Huber | + | [[Category: Huber K]] |
| - | [[Category: Kopec | + | [[Category: Kopec J]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | [[Category: Shrestha | + | [[Category: Shrestha L]] |
| - | [[Category: Srikannathasan | + | [[Category: Srikannathasan V]] |
| - | [[Category: Szykowska | + | [[Category: Szykowska A]] |
| - | [[Category: Talon | + | [[Category: Talon R]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
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| - | + | ||
Current revision
Crystal structure of human Spindlin-2B protein in complex with ART(M3L)QTA(2MR)KS peptide
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Burgess-Brown N | Edwards AM | Gileadi C | Huber K | Kopec J | Oppermann U | Shrestha L | Srikannathasan V | Szykowska A | Talon R | Von Delft F
