5uzs

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==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200==
==Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200==
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<StructureSection load='5uzs' size='340' side='right' caption='[[5uzs]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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<StructureSection load='5uzs' size='340' side='right'caption='[[5uzs]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5uzs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clop1 Clop1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UZS FirstGlance]. <br>
<table><tr><td colspan='2'>[[5uzs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clop1 Clop1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5UZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5UZS FirstGlance]. <br>
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
[[http://www.uniprot.org/uniprot/A0A0H2YRZ7_CLOP1 A0A0H2YRZ7_CLOP1]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
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==See Also==
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*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Clop1]]
[[Category: Clop1]]
[[Category: IMP dehydrogenase]]
[[Category: IMP dehydrogenase]]
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[[Category: Large Structures]]
[[Category: Anderson, W F]]
[[Category: Anderson, W F]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]

Revision as of 09:25, 1 January 2020

Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200

PDB ID 5uzs

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