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2awb

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[[Image:2awb.gif|left|200px]]
[[Image:2awb.gif|left|200px]]
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{{Structure
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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{{STRUCTURE_2awb| PDB=2awb | SCENE= }}
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|RELATEDENTRY=[[2avy|2AVY]], [[2aw4|2AW4]], [[2aw7|2AW7]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2awb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2awb OCA], [http://www.ebi.ac.uk/pdbsum/2awb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2awb RCSB]</span>
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'''Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. This file contains the 50S subunit of the second 70S ribosome. The entire crystal structure contains two 70S ribosomes and is described in remark 400.'''
'''Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. This file contains the 50S subunit of the second 70S ribosome. The entire crystal structure contains two 70S ribosomes and is described in remark 400.'''
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[[Category: Zhang, W.]]
[[Category: Zhang, W.]]
[[Category: 50s ribosomal subunit]]
[[Category: 50s ribosomal subunit]]
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[[Category: rna-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:32:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:58:07 2008''
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Revision as of 16:32, 3 May 2008

Image:2awb.gif

Template:STRUCTURE 2awb

Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. This file contains the 50S subunit of the second 70S ribosome. The entire crystal structure contains two 70S ribosomes and is described in remark 400.


Overview

We describe two structures of the intact bacterial ribosome from Escherichia coli determined to a resolution of 3.5 angstroms by x-ray crystallography. These structures provide a detailed view of the interface between the small and large ribosomal subunits and the conformation of the peptidyl transferase center in the context of the intact ribosome. Differences between the two ribosomes reveal a high degree of flexibility between the head and the rest of the small subunit. Swiveling of the head of the small subunit observed in the present structures, coupled to the ratchet-like motion of the two subunits observed previously, suggests a mechanism for the final movements of messenger RNA (mRNA) and transfer RNAs (tRNAs) during translocation.

About this Structure

2AWB is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structures of the bacterial ribosome at 3.5 A resolution., Schuwirth BS, Borovinskaya MA, Hau CW, Zhang W, Vila-Sanjurjo A, Holton JM, Cate JH, Science. 2005 Nov 4;310(5749):827-34. PMID:16272117 Page seeded by OCA on Sat May 3 19:32:58 2008

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