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4han

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==Crystal structure of Galectin 8 with NDP52 peptide==
==Crystal structure of Galectin 8 with NDP52 peptide==
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<StructureSection load='4han' size='340' side='right' caption='[[4han]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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<StructureSection load='4han' size='340' side='right'caption='[[4han]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4han]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HAN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4han]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HAN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CALCOCO2, NDP52 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4han FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4han OCA], [https://pdbe.org/4han PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4han RCSB], [https://www.ebi.ac.uk/pdbsum/4han PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4han ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4han FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4han OCA], [http://pdbe.org/4han PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4han RCSB], [http://www.ebi.ac.uk/pdbsum/4han PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4han ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref> [[http://www.uniprot.org/uniprot/CACO2_HUMAN CACO2_HUMAN]] May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion.<ref>PMID:17635994</ref>
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[https://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4han" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4han" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Galectin 3D structures|Galectin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Hong, S B]]
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[[Category: Large Structures]]
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[[Category: Kim, B W]]
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[[Category: Hong SB]]
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[[Category: Kim, J H]]
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[[Category: Kim B-W]]
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[[Category: Kwon, D H]]
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[[Category: Kim JH]]
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[[Category: Song, H K]]
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[[Category: Kwon DH]]
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[[Category: Autophagy]]
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[[Category: Song HK]]
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[[Category: Autophagy adapter molecule]]
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[[Category: Cytosol]]
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[[Category: Innate immunity]]
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[[Category: Nad binding]]
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[[Category: Ndp52 peoptide binding]]
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[[Category: Sugar binding protein]]
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Revision as of 08:07, 3 November 2022

Crystal structure of Galectin 8 with NDP52 peptide

PDB ID 4han

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