This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4n1d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:26, 28 December 2022) (edit) (undo)
 
Line 1: Line 1:
==Nodal/BMP2 chimera NB250==
==Nodal/BMP2 chimera NB250==
-
<StructureSection load='4n1d' size='340' side='right' caption='[[4n1d]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
+
<StructureSection load='4n1d' size='340' side='right'caption='[[4n1d]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4n1d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N1D FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4n1d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N1D FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BMP2, BMP2A, Nodal ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1d OCA], [https://pdbe.org/4n1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n1d RCSB], [https://www.ebi.ac.uk/pdbsum/4n1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1d ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n1d OCA], [http://pdbe.org/4n1d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n1d RCSB], [http://www.ebi.ac.uk/pdbsum/4n1d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n1d ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/NODAL_HUMAN NODAL_HUMAN] Septopreoptic holoprosencephaly;Situs ambiguus;Semilobar holoprosencephaly;Lobar holoprosencephaly;Situs inversus totalis;Alobar holoprosencephaly;Midline interhemispheric variant of holoprosencephaly;Microform holoprosencephaly. The disease is caused by variants affecting the gene represented in this entry.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/BMP2_HUMAN BMP2_HUMAN]] Induces cartilage and bone formation.
+
[https://www.uniprot.org/uniprot/NODAL_HUMAN NODAL_HUMAN] Essential for mesoderm formation and axial patterning during embryonic development.[https://www.uniprot.org/uniprot/BMP2_HUMAN BMP2_HUMAN] Induces cartilage and bone formation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 19:
</div>
</div>
<div class="pdbe-citations 4n1d" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4n1d" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Bone morphogenetic protein 3D structures|Bone morphogenetic protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Esquivies, L]]
+
[[Category: Large Structures]]
-
[[Category: Cytokine]]
+
[[Category: Esquivies L]]
-
[[Category: Signaling protein]]
+

Current revision

Nodal/BMP2 chimera NB250

PDB ID 4n1d

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools