5b61
From Proteopedia
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b61 OCA], [http://pdbe.org/5b61 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b61 RCSB], [http://www.ebi.ac.uk/pdbsum/5b61 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b61 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b61 OCA], [http://pdbe.org/5b61 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b61 RCSB], [http://www.ebi.ac.uk/pdbsum/5b61 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b61 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Stability of green fluorescent protein (GFP) is sometimes important for a proper practical application of this protein. Random mutagenesis and targeted mutagenesis have been used to create better-folded variants of GFP, including recently reported extra-superfolder GFP. Our aim was to determine the crystal structure of extra-superfolder GFP, which is more robustly folded and stable than GFP and superfolder GFP. The structural and structure-based mutagenesis analyses revealed that some of the mutations that created extra-superfolder GFP (F46L, E126K, N149K, and S208L) contribute to folding robustness by stabilizing extra-superfolder GFP with various noncovalent bonds. | ||
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| + | The mechanism of folding robustness revealed by the crystal structure of extra-superfolder GFP.,Choi JY, Jang TH, Park HH FEBS Lett. 2017 Jan;591(2):442-447. doi: 10.1002/1873-3468.12534. Epub 2016 Dec, 28. PMID:27990640<ref>PMID:27990640</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5b61" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Green Fluorescent Protein|Green Fluorescent Protein]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:28, 26 December 2018
Extra-superfolder GFP
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