5n74
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Microtubule end binding protein complex== | ==Microtubule end binding protein complex== | ||
| - | <StructureSection load='5n74' size='340' side='right' caption='[[5n74]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='5n74' size='340' side='right'caption='[[5n74]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5n74]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Galago_garnetti Galago garnetti] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N74 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N74 FirstGlance]. <br> | <table><tr><td colspan='2'>[[5n74]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Galago_garnetti Galago garnetti] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5N74 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5N74 FirstGlance]. <br> | ||
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPRE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=30611 Galago garnetti])</td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPRE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=30611 Galago garnetti]), KAR9, YPL269W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n74 OCA], [http://pdbe.org/5n74 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n74 RCSB], [http://www.ebi.ac.uk/pdbsum/5n74 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n74 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5n74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5n74 OCA], [http://pdbe.org/5n74 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5n74 RCSB], [http://www.ebi.ac.uk/pdbsum/5n74 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5n74 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN]] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref> [[http://www.uniprot.org/uniprot/KAR9_YEAST KAR9_YEAST]] Involved in karyogamy. Component of a cortical adaptor complex that orients cytoplasmic microtubules. It may be involved in anchoring cytoplasmic microtubules to the cell cortex. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 24: | ||
[[Category: Galago garnetti]] | [[Category: Galago garnetti]] | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Kumar, A]] | [[Category: Kumar, A]] | ||
[[Category: Steinmetz, M]] | [[Category: Steinmetz, M]] | ||
[[Category: Microtubule binding protein]] | [[Category: Microtubule binding protein]] | ||
[[Category: Microtubule end binding protein complex]] | [[Category: Microtubule end binding protein complex]] | ||
Revision as of 07:47, 11 March 2020
Microtubule end binding protein complex
| |||||||||||
