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5jgp

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Current revision (07:39, 8 March 2023) (edit) (undo)
 
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==Crystal structure of the nitrate/nitrite sensor NarQ fragment bound with iodide ions==
==Crystal structure of the nitrate/nitrite sensor NarQ fragment bound with iodide ions==
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<StructureSection load='5jgp' size='340' side='right' caption='[[5jgp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='5jgp' size='340' side='right'caption='[[5jgp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jgp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JGP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JGP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jgp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JGP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iji|5iji]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jgp OCA], [https://pdbe.org/5jgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jgp RCSB], [https://www.ebi.ac.uk/pdbsum/5jgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jgp ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">narQ, b2469, JW2453 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jgp OCA], [http://pdbe.org/5jgp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jgp RCSB], [http://www.ebi.ac.uk/pdbsum/5jgp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jgp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NARQ_ECOLI NARQ_ECOLI]] Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the NarL/NarP proteins. NarQ probably activates NarL and NarP by phosphorylation. NarQ probably negatively regulates the NarL protein by dephosphorylation.
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[https://www.uniprot.org/uniprot/NARQ_ECOLI NARQ_ECOLI] Acts as a sensor for nitrate/nitrite and transduces signal of nitrate/nitrite availability to the NarL/NarP proteins. NarQ probably activates NarL and NarP by phosphorylation. NarQ probably negatively regulates the NarL protein by dephosphorylation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
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[[Category: Gordeliy, V]]
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[[Category: Gordeliy V]]
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[[Category: Melnikov, I]]
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[[Category: Melnikov I]]
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[[Category: Polovinkin, V]]
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[[Category: Polovinkin V]]
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[[Category: Popov, A]]
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[[Category: Popov A]]
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[[Category: Iodide]]
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[[Category: Membrane protein]]
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[[Category: Sensor]]
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[[Category: Signaling protein]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the nitrate/nitrite sensor NarQ fragment bound with iodide ions

PDB ID 5jgp

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