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4rfl

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==Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii==
==Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii==
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<StructureSection load='4rfl' size='340' side='right' caption='[[4rfl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4rfl' size='340' side='right'caption='[[4rfl]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rfl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RFL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RFL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rfl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RFL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">egsA, MJ0712 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rfl OCA], [https://pdbe.org/4rfl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rfl RCSB], [https://www.ebi.ac.uk/pdbsum/4rfl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rfl ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/sn-glycerol-1-phosphate_dehydrogenase sn-glycerol-1-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.261 1.1.1.261] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rfl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rfl OCA], [http://pdbe.org/4rfl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rfl RCSB], [http://www.ebi.ac.uk/pdbsum/4rfl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rfl ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA]] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
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[https://www.uniprot.org/uniprot/G1PDH_METJA G1PDH_METJA] Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Metja]]
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[[Category: Large Structures]]
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[[Category: Sn-glycerol-1-phosphate dehydrogenase]]
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[[Category: Methanocaldococcus jannaschii DSM 2661]]
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[[Category: Carbone, V]]
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[[Category: Carbone V]]
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[[Category: Ronimus, R S]]
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[[Category: Ronimus RS]]
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[[Category: Schofield, L R]]
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[[Category: Schofield LR]]
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[[Category: Sutherland-Smith, A J]]
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[[Category: Sutherland-Smith AJ]]
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[[Category: Dehydrogenase]]
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[[Category: Oxidoreductase]]
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[[Category: Rossman fold metal ion binding]]
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Revision as of 06:53, 2 March 2023

Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii

PDB ID 4rfl

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