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4ua1
From Proteopedia
(Difference between revisions)
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==Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion== | ==Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion== | ||
| - | <StructureSection load='4ua1' size='340' side='right' caption='[[4ua1]], [[Resolution|resolution]] 2.56Å' scene=''> | + | <StructureSection load='4ua1' size='340' side='right'caption='[[4ua1]], [[Resolution|resolution]] 2.56Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ua1]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4ua1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UA1 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ua1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ua1 OCA], [https://pdbe.org/4ua1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ua1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ua1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ua1 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q799U3_PRIMG Q799U3_PRIMG] Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.[ARBA:ARBA00024874] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 4ua1" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ua1" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Priestia megaterium]] |
| - | [[Category: | + | [[Category: Chan NL]] |
| - | [[Category: | + | [[Category: Chang CC]] |
| - | [[Category: | + | [[Category: Huang CC]] |
| - | [[Category: | + | [[Category: Lin LY]] |
| - | [[Category: | + | [[Category: Zou XW]] |
| - | + | ||
Revision as of 08:11, 22 March 2023
Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion
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Categories: Large Structures | Priestia megaterium | Chan NL | Chang CC | Huang CC | Lin LY | Zou XW
