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Cryptochrome

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Line 21: Line 21:
[[4ct0]] – mCry-1 + PER2 <br />
[[4ct0]] – mCry-1 + PER2 <br />
[[4i6g]] – mCry-2 + FAD <br />
[[4i6g]] – mCry-2 + FAD <br />
 +
[[4i6j]] – mCry-2 + F-box/LRR repeat protein + S-phase kinase-associated protein <br />
[[4u8h]] – mCry-2 + PER2 <br />
[[4u8h]] – mCry-2 + PER2 <br />
[[4mlp]] – mCry-2 + carbazol derivative <br />
[[4mlp]] – mCry-2 + carbazol derivative <br />

Revision as of 06:57, 16 April 2018

Mouse cryptochrome-1 complex with FAD (PDB code 4i6g)

Drag the structure with the mouse to rotate

3D Structures of cryptochrome

Updated on 16-April-2018

4i6e, 4k0r, 5t5x – mCry-1 – mouse
4jzy, 4gu5, 4k03 – Cry-1 + FAD – Drosophila melanogaster
1u3c – AtCry-1 PHR domain + FAD - Arabidopsis thaliana
1u3d – AtCry-1 PHR domain + FAD + AMPPNP
4ct0 – mCry-1 + PER2
4i6g – mCry-2 + FAD
4i6j – mCry-2 + F-box/LRR repeat protein + S-phase kinase-associated protein
4u8h – mCry-2 + PER2
4mlp – mCry-2 + carbazol derivative
3zxs – Cry-2 + FAD – Rhodobacter sphaeroides
2j4d, 2ijg – AtCry-3 + FAD
2vtb – AtCry-3 + FAD + DNA
3fy4 – AtCry 6-4 + FAD
1np7 – Cry - Synechocystis

References

  1. Yoshii T, Todo T, Wulbeck C, Stanewsky R, Helfrich-Forster C. Cryptochrome is present in the compound eyes and a subset of Drosophila's clock neurons. J Comp Neurol. 2008 Jun 20;508(6):952-66. doi: 10.1002/cne.21702. PMID:18399544 doi:http://dx.doi.org/10.1002/cne.21702
  2. Narasimamurthy R, Hatori M, Nayak SK, Liu F, Panda S, Verma IM. Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12662-7. doi:, 10.1073/pnas.1209965109. Epub 2012 Jul 9. PMID:22778400 doi:http://dx.doi.org/10.1073/pnas.1209965109

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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