This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5yni
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG== | |
| - | + | <StructureSection load='5yni' size='340' side='right' caption='[[5yni]], [[Resolution|resolution]] 2.07Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yni]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YNI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YNI FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTG:7-METHYL-GUANOSINE-5-TRIPHOSPHATE-5-GUANOSINE'>GTG</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yni OCA], [http://pdbe.org/5yni PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yni RCSB], [http://www.ebi.ac.uk/pdbsum/5yni PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yni ProSAT]</span></td></tr> |
| - | [[Category: Ke, Z | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/K4LC41_9BETC K4LC41_9BETC]] Nsp7-nsp8 hexadecamer may possibly confer processivity to the polymerase, maybe by binding to dsRNA or by producing primers utilized by the latter (By similarity).[SAAS:SAAS014829_004_014545] Nsp9 is a ssRNA-binding protein (By similarity).[SAAS:SAAS014829_004_001449] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chen, Y]] | ||
| + | [[Category: Fan, C P]] | ||
| + | [[Category: Guo, D Y]] | ||
| + | [[Category: Ke, Z H]] | ||
| + | [[Category: Wei, S M]] | ||
[[Category: Yang, L]] | [[Category: Yang, L]] | ||
| - | [[Category: | + | [[Category: Complex]] |
| - | [[Category: | + | [[Category: Inhibitor]] |
| - | [[Category: | + | [[Category: Transferase]] |
Revision as of 06:27, 5 December 2018
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppG
| |||||||||||
Categories: Chen, Y | Fan, C P | Guo, D Y | Ke, Z H | Wei, S M | Yang, L | Complex | Inhibitor | Transferase
