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5yno
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppA== | |
| - | + | <StructureSection load='5yno' size='340' side='right' caption='[[5yno]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yno]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YNO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YNO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTA:P1-7-METHYLGUANOSINE-P3-ADENOSINE-5,5-TRIPHOSPHATE'>GTA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yno FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yno OCA], [http://pdbe.org/5yno PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yno RCSB], [http://www.ebi.ac.uk/pdbsum/5yno PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yno ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/K4LC41_9BETC K4LC41_9BETC]] Nsp7-nsp8 hexadecamer may possibly confer processivity to the polymerase, maybe by binding to dsRNA or by producing primers utilized by the latter (By similarity).[SAAS:SAAS014829_004_014545] Nsp9 is a ssRNA-binding protein (By similarity).[SAAS:SAAS014829_004_001449] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fan, C P]] | ||
| + | [[Category: Guo, D Y]] | ||
| + | [[Category: Ke, Z H]] | ||
| + | [[Category: Wei, S M]] | ||
| + | [[Category: Yang, L]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:28, 5 December 2018
Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAH and m7GpppA
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Categories: Fan, C P | Guo, D Y | Ke, Z H | Wei, S M | Yang, L | Complex | Inhibitor | Transferase
